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Adams, David S.
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Major Qualifying Projects
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Worcester Polytechnic Institute
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Major Qualifying Project
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In Situ Analysis of RNAi Using Affymetrix' ViewRNA System
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Complement Receptor-1 Binding to Erythrocytes Under Normal and Pathological Membrane Deforming Conditions
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A Novel Role of the p53 Tumor Suppressor Pathway in Maintaining Glucose Homeostasis
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MicroRNA “SPONGE”: PROOF OF CONCEPT FOR A NOVEL MicroRNA TARGET IDENTIFICATION TECHNIQUE
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Mechanism of Activation of Anti-HCMV Nucleoside Analog MBX 2168
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Increasing the Efficiency of Monoclonal Antibody Production by Isolating Splenic B Cells in Advance of Hybridoma Fusion
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MUTAGENESIS OF HUMAN SUPERVILLIN’S ADHESION SEQUENCE IDENTIFIES CHANGES IN THE NUMBER
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Interaction of Zinc Finger Proteins 146 & 507 with the Transposable Element LINE-1
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MUTATION SCREENING OF CANDIDATE BREAST CANCER SUSCEPTIBILITY GENES IN NON-BRCA1/2 FAMILIES
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Lipopolysaccharide Induced Apoptosis in Rat Hepatocytes
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VALIDATION OF PHARMACEUTICALS LEADING TO THE REDUCTION OF INCLUSION OF TAU EXON 10
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Inhibition of HIV-1 Tat Induced Inflammation by the NF-kB Subunit RelB
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Yeast two-hybrid of PIE-1 in C. elegans
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Use of HIV-1 2-ltr circle sequences as a predictor of drug-induced mutations
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Upregulation of Neuronal Growth Genes During a Therapy for Rat Spinal Cord Injury
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Understanding the function of SFRP-1, a Wnt antagonist, in the development of murine skeletal tissue
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Transforming growth factor- and prostate cancer
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The role of XRCC3 in homologous recombination
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The role of Flt3/Flk2 in B cell development
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The Presence of DNA-binding protein LSF in a complex that binds to the switch region of immunoglobulin heavy chain gene gamma 3
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The effects of circadian rhythm and low-dose irradiation (100cGy) on murine bone marrow transplantation
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The effect of a dominant-negative RIP-K45A on TNF-stimulated L929 cells
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The Activator protein-1 upregulated by neurotrophic peptides NMI-9236 and NMI-8933 is capable of transcriptional trans-activation
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Syntaxin 1A functions as the sufficient T-SNARE for spontaneous fusion of bovine NSG to a planar lipid bilayer
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STATs are involved in T-cell development downstream of IL-7 receptor
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Small peptide substitutes for full-length neurotrophic factors
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Small peptide substitutes for full-length ependymin neurotrophic factor up-regulate SOD, which is part of the cell's natural response to anoxia
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Small peptide substitutes for full-length ependymin neurotrophic factor up-regulate SOD
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SHP2 tyrosine phosphatase association with endothelial plasma membranes is regulated by cholesterol
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Sequence analysis of CP and NCP HIV-1 clones
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Selective amplification of cryopreserved human umbilical cord blood stem cells
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Roll of factors and interacting proteins in Cbfa1 function
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Ribozyme viral infection of Hct116 cells
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Rescue of a nonfunctional Newcastle disease hemagglutinin-neuraminidase protein by mutation of key residues residing at the dimer interface
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Regulation of Runx genes during mesenchymal chondrogenesis
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Regulation of osteoblast differentiation by Msx2 and Dix3 homeodomain transcription factors
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Protein kinase assay development and compound characterization using HTRF technology
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Prohormone convertase 2 as a biomarker for neuroendocrine lung tumors -- detection of gene products in PreservCyt solutions
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Production of biologically active CDK inhibitors p21 and p27 as TAT-fusion proteins
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Production of antibodies against specific neurotransmitter receptors
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Production of a putative mouse homolog for Protein AS160 and its use for antibody formulation for studying GLUT4 trafficking in adipocytes
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Production of a NGF-TV A fusion protein for the potential targeting of an ALV-pseudotyped lentivirus to neuronal cells
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Post-operative pain
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Peptides mimicking neurotrophic factors effective in treating neurodegenerative disorders upregulate anti-oxidative enzymes.
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Nuclear import of HIV-1 -- optimizing siRNA techniques
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Neurotrophic peptides that are therapeutic for strokes in a rat model upregulate enzymes which reduce oxidative stress in various tissues
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Neuronal-like differentiation of human umbilical cord blood stem cells
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Mutational analysis of the neuraminidase activity of the Newcastle Disease HN protein
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Mutational analysis of the HR2 lysine rich strip in the Newcastle disease virus fusion protein
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Movement of the inactivating chromosome to the heterochromatic compartment is coincident with the irreversibility of the inactivation process
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