In the moss Physcomitrella patens, myosin XI mediated polarized tip growth is essential for growth and expansion. It has been hypothesized that, during polarized growth, secretory vesicles move to the tip of the expanding cell via an interaction between the myosin XI globular tail and RabA4. In this study, we show that several mutations in the putative binding region for RabA4 on the myosin XI tail produce the same phenotype as a myosin XIa knockdown, suggesting an interaction with RabA4.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Armstrong, Erin Lynn

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042512-135727

Advisor

• Vidali, Luis

Year

• 2012

Date created

• 2012-04-25

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Source

• E-project-042512-135727

Rights statement

• In Copyright

Last modified

• 2024-03-04