Because of the interest in auto-immune inflammatory diseases by Abbott Bioresearch Center, and the prominence of protein kinases and their pathways in the cause of some diseases, it is the hope that inhibition of a particular chosen kinase will cure a specific inflammatory disease. This project will describe the initial steps of a target's characterization, and the search for a specific compound that demonstrates specific inhibition against our target without dramatic inhibition of other prominent and related kinases through the usage of HTRF Technology.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Clark, Kevin Michael

Publisher

• Worcester Polytechnic Institute

Identifier

• 03A009M

Advisor

• Adams, David S.

Year

• 2003

Sponsor

• Abbott Bioresearch Center

Date created

• 2003-01-01

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright