The nematode, Caenorhabditis elegans, was used to study the function of genes involved in neurological development. The gene mig-10 is necessary for IL2 neurons to properly connect to the worm's brain. Using PCR, constructs were made containing various segments of the mig-10 gene and GFP (Green Fluorescent Protein) to study the mig-10 promoter::GFP and MIG-10 protein expression patterns. A transgenic strain to study mig-10 promoter::GFP expression was obtained and initially characterized. One putative line was generated using mig-10::GFP rescuing constructs.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Rivard, Maegan Veronica

Publisher

• Worcester Polytechnic Institute

Identifier

• 01D319M

Advisor

• Ryder, Elizabeth F.

Year

• 2001

Sponsor

• Pfizer, Inc

Date created

• 2001-01-01

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright