Antibiotic resistance has increased for many different diseases including tuberculosis. Scientists have begun to seek ways and places to discover new antibiotics to combat this resistance. Studies over the last 60 years suggest that pathogen-inhibiting bacteria can be found in soil. A number of bacterial isolates potentially producing antibiotic compounds have been found in the soil by students in the Microbes to Molecules laboratory course at Worcester Polytechnic Institute (WPI). This project tested those isolates for the ability to inhibit the growth of Mycobacterium smegmatis, a model bacteria for Mycobacterium tuberculosis. The goal of the project described here was to identify isolates capable of inhibiting M. smegmatis and determine the mechanism(s) of inhibition.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Barter, Megan Victoria
• McCarron, Christine Roberta

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042717-163632

Advisor

• Shell, Scarlet
• Buckholt, Michael Allan

Year

• 2017

Date created

• 2017-04-27

地点

• Worcester

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright