A solution containing 0.03 or 0.08 g/ml tetracycline HCI and 0.10 g/ml poly(vinyl-alcohol) was electrospun onto a surgical stent, aluminum alloy cylinders, and freeze dried in a mold. The drug elution of tetracycline from the samples was measured in a 37C PBS bath through spectrophotometry. The diffusivity value for the stent was found to be 3.3 x 10 (m/s), whereas the values for the cylinders and freeze dried samples were 4.73 x 10 and 3.3 x 10 m/s), respectively.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Saviski, Michelle M.
• Vadakekalam, Jacob
• Seward, Matthew John

Publisher

• Worcester Polytechnic Institute

Identifier

• 06D296M

Advisor

• Shivkumar, Satya

Year

• 2006

Date created

• 2006-01-01

Resource type

• Major Qualifying Project

Major

• Biomedical Engineering

Rights statement

• In Copyright