Student Work

Reproductive experience increases estrogen induced prolactin secretion in female rats

Public

Downloadable Content

open in viewer

Since prolactin secretion decreases with parity, we investigated estradiol's effects on its secretion. Two groups of age matched rats were ovariectomized, then challenged with 5 or 25 up/kg estrogen. Serum prolactin levels were determined by radioimmunoassay. Prolactin levels in primiparous females increased significantly at 5 ug/kg estradiol. While levels in nulliparous females show a dose responsive change, it was not significant. These findings may indicate an altered sensitivity to estrogen in dopaminergic control of prolactin secretion.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
Creator
Publisher
Identifier
  • 03D074M
Advisor
Year
  • 2003
Date created
  • 2003-01-01
Resource type
Major
Rights statement
License

Relations

In Collection:

Items

Items

Permanent link to this page: https://digital.wpi.edu/show/5138jh84j