Student Work
Reproductive experience increases estrogen induced prolactin secretion in female rats
PublicSince prolactin secretion decreases with parity, we investigated estradiol's effects on its secretion. Two groups of age matched rats were ovariectomized, then challenged with 5 or 25 up/kg estrogen. Serum prolactin levels were determined by radioimmunoassay. Prolactin levels in primiparous females increased significantly at 5 ug/kg estradiol. While levels in nulliparous females show a dose responsive change, it was not significant. These findings may indicate an altered sensitivity to estrogen in dopaminergic control of prolactin secretion.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Publisher
- Identifier
- 03D074M
- Advisor
- Year
- 2003
- Date created
- 2003-01-01
- Resource type
- Major
- Rights statement
- License
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