. . . "Worcester Polytechnic Institute" . . "1999" . "http://rightsstatements.org/vocab/InC/1.0/" . "This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review." . . "Gibson, Daniel G." . "StudentWork" . "2021-09-14T13:28:25.707899301-04:00"^^ . "99D141M" . "depositor@wpi.edu" . . "Perry, Leigh Ann" . "1999-01-01" . . "Tufts University School of Veterinary Medicine" . "Bile acid-induced apoptosis in a MDCK cell line transfected with the hepatocyte sinusoidal bile acid transporter" . "Major Qualifying Project" . "Biology & Biotechnology" . . "The objective of this project is to determine if the canine kidney cell line (MDCK) transfected with the gene for the hepatocyte sinusoidal transporter (Ntcp) would be a useful model for rat hepatocytes in studying bile acid-induced apoptosis. In order to verify this cell line as a beneficial model, several experiments involving bile acids and cyclic adenine monophosphate were performed. A comparison of these results with those performed on hepatocytes indicate that MDCKs are valuable in studying bile acid-induced apoptosis." . . "ActiveFedora::Aggregation::ListSource" . . . . .