TY - RPRT A1 - Perry, Leigh Ann AB - The objective of this project is to determine if the canine kidney cell line (MDCK) transfected with the gene for the hepatocyte sinusoidal transporter (Ntcp) would be a useful model for rat hepatocytes in studying bile acid-induced apoptosis. In order to verify this cell line as a beneficial model, several experiments involving bile acids and cyclic adenine monophosphate were performed. A comparison of these results with those performed on hepatocytes indicate that MDCKs are valuable in studying bile acid-induced apoptosis. DA - 1999/01/01 DB - Digital WPI DP - Worcester Polytechnic Institute ID - 99D141M L1 - https://digital.wpi.edu/show/5h73q0106 LK - https://digital.wpi.edu/ PB - Worcester Polytechnic Institute PY - 1999 T1 - Bile acid-induced apoptosis in a MDCK cell line transfected with the hepatocyte sinusoidal bile acid transporter UR - https://digital.wpi.edu/show/df65vb78w ER -