Student Work

Synthesis of Novel Materials Containing Catechol Bioisosteres

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The "photoinitiated intramolecular ylide-alkene cycloaddition reaction" which was developed in our laboratory provides a method for construction of up to three rings and six chiral centers in a single experimental operation from relatively simple starting materials. This project has attempted to utilize this reaction to quickly synthesize novel materials which incorporate catechol bioisosteres into the organic scaffold in the hopes of imparting potentially useful bio-activity to the new molecules.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
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Identifier
  • E-project-042208-233933
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Year
  • 2008
Date created
  • 2008-04-22
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