Student Work

Sequence and expression analysis of Caenorhabditis elegans srf-6 candidate gene F41G3.10

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Mutations in the C. elegans gene srf-6 result in the constitutive display of a surface antigen normally displayed only in the L1 developmental stage. To determine the location of these mutations, an extensive DNA sequence analysis of a candidate gene region, previously shown to partially rescue srf-6, was undertaken for each of 8 identified mutants. An additional mutant, produced by transposon insertion, was stabilized by back-crossing. Finally, a transcriptional analysis was performed to determine the exon/intron pattern of the candidate gene.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
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  • 03D152M
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  • 2003
Date created
  • 2003-01-01
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