This project focuses on SARS coronavirus infection. Immunofluorescence microscopy was used to locate several factors that could help in investigating SARS pathology. The locations of two cytokines were investigated in relation to SARS CoV infected cells. Infected cells were also stained to determine their cell type. SARS CoV infected cells did not stain positive for macrophage or epithelial cell markers. SARS CoV infected cells were also not producing TGF-beta or TNF-alpha, two prominent cytokines involved with inflammation. These results will be used to design in vitro experiments to further examine SARS CoV infection.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Hayden, Matthew Steven

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-011105-155641

Advisor

• Adams, David S.

Year

• 2005

Sponsor

• Biology & Biotechnology

Date created

• 2005-01-11

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright