In one synthetic route toward analogs of Huperzine, a natural potent reversible inhibitor of acetylcholinesterase, key heteroatom directed photoarylation reaction is predicted to form the central skeleton in one step from an easily synthesized precursor. Earlier attempts to effect this photoarylation in pyridine systems were not successful. The goal of this project is to develop systems or procedures to successfully effect this key step.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Kormos, Chad Michael

Publisher

• Worcester Polytechnic Institute

Identifier

• 04D117M

Advisor

• Dittami, James P.

Year

• 2004

Date created

• 2004-01-01

Resource type

• Major Qualifying Project

Major

• Chemistry

Rights statement

• In Copyright