The National Cancer Institute previously performed a high throughput screening to identify over 88,000 extracts with anticancer properties. This project aims to improve upon this screening system and develop a high-throughput screening system with the use of plant cell extracts to produce more reliable and consistent results, which can potentially lead to the discovery of novel specialized metabolites. By optimizing the solvent concentration and verifying the effects of known paclitaxel compounds, we were able to assess the effects of the Taxus cultures to further verify the effectiveness of our screening platform.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Addai, Michelle
• Opare-Sem, Yaw
• Bidon, Miya Kristine Rubio

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042618-151828

Advisor

• Roberts, Susan Celia

Year

• 2018

Date created

• 2018-04-26

Resource type

• Major Qualifying Project

Major

• Chemical Engineering

Rights statement

• In Copyright

Last modified

• 2020-11-14