Student Work

MIG-10 and UNC-53: two proteins involved in neuron migration and excretory canal outgrowth

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Mutations in mig-10 and unc-53 in C. elegans result in defects in axon guidance and excretory canal outgrowth. To better understand these genes' effects on migration and outgrowth, single and double mutant phenotypes were compared. In mig-10 mutants, excretory canal truncation is first observed during embryogenesis. Rescue experiments show that MIG-10 functions cell autonomously in the excretory cell. Phenotypes of single and double mutants suggest that mig-10 and unc-53 may have varying functions in different cells.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
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  • E-project-042711-150421
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Year
  • 2011
Date created
  • 2011-04-27
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