A new subtype of estrogen receptor (ER) ER- has recently been shown to exist in rat prostate cancer cells. But, ER- has not currently [been] detected in human prostate cancer cells. To prove the existence of this new receptor subtype in human prostate cancer cells, three types of human prostate cancer cell lines and one fibroblast cell line were treated with estrogen and anti-estrogen and cell proliferation was measured. The results indicate that ER- exists in human prostate cancer cells.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Shen, Yue

Publisher

• Worcester Polytechnic Institute

Identifier

• 00D076M

Advisor

• Adams, David S.

Year

• 2000

Date created

• 2000-01-01

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright