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Vessel Ring Bioreactor Public

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Cyclic loading is an important stimulus for creating mechanically stable tissue engineered blood vessels. The goal of this work is to create a device that dynamically conditions rings of vascular tissue created by cells in culture without the use of a scaffold. To create a high-throughput and accurate yet inexpensive device, a regulated pressure source and electronic valve controller were utilized to cyclically inflate up to 32 ring segments cultured on a series of silicone tubes encased in standard sterile conical tubes. This device will be used to determine the dynamic culture conditions that optimize engineered vessel growth and maturation in culture.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
Last modified
  • 02/02/2021
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  • E-project-043009-121244
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  • 2009
Date created
  • 2009-04-30
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