Modified Dextran Polymers for Drug Delivery
公开A collaboration between WPI and ENSIC was undertaken to investigate the properties of emulsions as a drug delivery system. Biocompatible amphiphilic polymers are used as emulsifiers for controlled drug delivery. They act as a barrier between phases in oil-in-water emulsions to increase stability. Oil soluble drugs can be encapsulated within the oil nanoparticles and released into a biological system. The goal of this project was to study modified dextran (DexC6), an amphiphilic polymer. The most stable emulsions were formed with a DexC6 aqueous concentration of 40g/L in a system of 40% octyldodecanol oil volume. Drug release kinetic experiments showed that encapsulated lidocaine is released at a slower rate than free lidocaine. Further research in emulsion drug delivery is recommended.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Creator
- Publisher
- Identifier
- E-project-042506-120742
- Advisor
- Year
- 2006
- Center
- Sponsor
- Date created
- 2006-04-25
- 地点
- Nancy
- Resource type
- Major
- Rights statement
关系
- 属于 Collection:
项目
单件
缩略图 | 标题 | 公开度 | Embargo Release Date | 行动 |
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Drug_Delivery_Final_MQP_2006.pdf | 公开 | 下载 | |
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Final_Drug_Delivery_Poster_2006.ppt | 公开 | 下载 |
Permanent link to this page: https://digital.wpi.edu/show/kw52j968f