The Signal Recognition Particle Receptor in the Endoplasmic Reticulum membrane involved in the co-translational pathway is the focus of this investigation. While the receptor has been sequenced, a domain of one of the subunits has an unknown structure. Several truncated forms of the protein were over expressed in E. Coli and purified. Circular Dichroism spectroscopy was used to determine the protein secondary structure of a domain of one of the subunits in the receptor.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Trueman, Steven F.

Publisher

• Worcester Polytechnic Institute

Identifier

• 04D026M

Advisor

• Argüello, José M.

Year

• 2004

Date created

• 2004-01-01

Resource type

• Major Qualifying Project

Major

• Biochemistry

Rights statement

• In Copyright