The goal of this study was to take the first step towards the development of an unobtrusive assay that would accurately measure embryo competency and viability. Its focus was to assess cell junction proteins in mouse embryos, due to their vital role in development. The junctional proteins investigated were E-cadherin, -catenin, ZO-1, occludin, desmocollin, and desmoplakin. Comparisons between in vivo and in vitro embryos were made. It was found that only E-cadherin and -catenin exhibited such a difference.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Hammond, Tara Noel
• Chisholm, John Alexander
• Jurofcik, Michelle Catherine

Publisher

• Worcester Polytechnic Institute

Identifier

• 99C035M

Advisor

• Rulfs, Jill

Year

• 1999

Sponsor

• Tufts N.E. Veterinary Medical Center

Date created

• 1999-01-01

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright