We present a programmable, custom engineered syringe pump that controls the delivery of two alternative media types to cells growing in standard microfluidic chambers. Our platform can multiplex parallel, independent, live-cell microscopy imaging experiments. We demonstrate the functionality of the multi-pump system by performing biological experiments that monitor the temporal dynamics of signaling inhibition in an important model melanoma cell line. Our system will allow researchers at the University of Massachusetts Medical School to perform their investigations on cellular response to dynamically changing environments.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Elhajjajy, Shaimae I.
• Karduss, Andrea

Publisher

• Worcester Polytechnic Institute

Identifier

• E-project-042618-131447

Advisor

• Albrecht, Dirk

Year

• 2018

Sponsor

• UMass Medical School

Date created

• 2018-04-26

Resource type

• Major Qualifying Project

Major

• Biomedical Engineering

Source

• E-project-042618-131447

Rights statement

• In Copyright

Última modificación

• 2024-05-13