Immobilization of Sarcosine Oxidase for use in creatinine biosensorsPublic
Downloadable Contentopen in viewer
Sarcosine oxidase is used in a three-enzyme cascade to detect levels of creatinine in human serum. This cascade can be immobilized within a biosensor for use in a blood analyzer. However, this sensor has a short use-life due to the diffusion and denaturation of the immobilized enzymes. The enzyme with the shorter lifespan within this sensor is sarcosine oxidase. This project investigates membranes that will immobilize sarcosine oxidase to prevent diffusion denaturation, thus extending the use-life of the sensors. The data indicates that PVA-sbq and MAPTAC 25 membranes serve as an excellent immobilizing media.
- This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
- Date created
- Resource type
- Rights statement
- In Collection:
|Thumbnail||Title||Visibility||Embargo Release Date||Actions|
Permanent link to this page: https://digital.wpi.edu/show/pk02cd731