Student Work

Understanding the function of SFRP-1, a Wnt antagonist, in the development of murine skeletal tissue

Öffentlich

SFRP-1 (Secreted Frizzled Related Protein-1), an antagonist of the Wnt signaling pathway, has been implicated in the regulation of a wide variety of developmental signaling processes. The purpose of this project was to characterize the embryonic spatio-temporal expression of SFRP-1 during murine embryonic development. SFRP-1 is expressed in a number of different tissue and cell types, including cartilage (round proliferating chondrocytes) and bone (osteoblasts), suggesting that SFRP-1 may play an important role in the regulation of murine skeletal development.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
Creator
Publisher
Identifier
  • 02D247M
Advisor
Year
  • 2002
Date created
  • 2002-01-01
Resource type
Major
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Permanent link to this page: https://digital.wpi.edu/show/qr46r377h