The synthesis of two chromophore-containing amino acids, N-Fmoc-L- pyrenylalanine and N-Fmoc-L- fluorenylalanine, residues that will be incorporated into a cyclic peptide, were undertaken. Model linear and cyclic peptides, into which these residues will be incorporated, were synthesized by a solid phase method. The cyclic peptides ability to self-assemble in solution through hydrogen bonding enables the formation of peptide nanotubes. Once formed, the long range energy or charge transfer of chromophore-containing cyclic peptides will be studied for possible device applications.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Dennen, Katherine Faye

Publisher

• Worcester Polytechnic Institute

Identifier

• 01D293M

Advisor

• McGimpsey, W. Grant

Year

• 2001

Date created

• 2001-01-01

Resource type

• Major Qualifying Project

Major

• Chemistry

Rights statement

• In Copyright