A potential non-invasive means for evaluating wound healing in vivo was investigated by characterizing the in-vitro bio-degradation of collagen sponges using MRI. Attempts to correlate measured MRI parameters with different degrees of collagen crosslinking were unsuccessful. Sodium alginate gels were also examined as a function of cross-linking (with Ca 2+) for alginate solutions of varying concentrations (0.18, 0.27, and 0.36M). The MRI-measured transverse relaxation rates and proton densities varied approximately linearly over this range of alginate concentrations.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Braveboy-Wagner, Justin Steven

Publisher

• Worcester Polytechnic Institute

Identifier

• 05E006M

Advisor

• Sotak, Christopher H.
• Peura, Robert A.

Year

• 2005

Date created

• 2005-01-01

Resource type

• Major Qualifying Project

Major

• International & Global Studies

Rights statement

• In Copyright