The dig-l gene is proposed to encode an adhesion molecule that plays an important role in the development of the C. elegans nervous system. To support dig-l's hypothesized location, the creation of large deletions in the gene, which are easier to locate than point mutations, was attempted, through animal exposure to gamma radiation. The animals' neurons were stained and subsequently examined under a microscope to screen putative mutants for the Dig-l phenotype. At least one mutant was successfully isolated.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Long, Daniel Josef

Publisher

• Worcester Polytechnic Institute

Identifier

• 01D321M

Advisor

• Ryder, Elizabeth F.

Year

• 2001

Sponsor

• UMass Medical Center, Worcester, MA

Date created

• 2001-01-01

Resource type

• Major Qualifying Project

Major

• Biology & Biotechnology

Rights statement

• In Copyright