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Synthesis and characterization of methyl pyrazoles Public

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The synthesis of 1,3,6-trimethyl-1H-pyrano [2,3-C]pyrazol-4one, 12 has been attempted. The initial steps involving the preparation of 1,3-dimethylpyrazolone 6 and C-acylation to yield 4-acetyl-5-hydroxy-1,3-dimethylpyrazole 9 were successfully carried out. Although the next step in the synthesis requires C-acylation of 9 at the methylketone side chain; only O-acylation was observed under a variety of conditions.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
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  • 03D030M
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  • 2003
Date created
  • 2003-01-01
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Permanent link to this page: https://digital.wpi.edu/show/ws859j901