Student Work

Transforming growth factor- and prostate cancer

Público

The purpose of this MQP was two-fold. First, to identify TGF- signaling pathways in PC3 cells and involvement of specific proteins such as PKC. Second, to discriminate between growth inhibitory and extracellular matrix inducing signaling pathways. This was accomplished using three experimental approaches: 1) Cell proliferation assays, 2) Signal transduction/gene expression assays, and 3) Western blot analysis identifying specific isoforms of down-regulated PKC. Although results of the first two approaches were inconclusive, cPKC was down regulated in response to PMA treatment.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
Creator
Publisher
Identifier
  • 99D117M
Advisor
Year
  • 1999
Sponsor
Date created
  • 1999-01-01
Resource type
Major
Rights statement

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