Huperzine A and B, alkaloids isolated from the club moss Huperzia serrata, are employed in traditional Chinese medicine to treat senile dementia and other ailments. Previous attempts to synthesize Huperzine analogs relying on a heteroatom directed photoarylation reaction encountered difficulties when a pyridine ring system was incorporated into the photoprecursor. This research seeks to develop an alternative to photochemical initiation of the heteroatom directed arylation employing microwave radiation.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Marineau, Jason Joseph

Publisher

• Worcester Polytechnic Institute

Identifier

• 04D268M

Advisor

• Dittami, James P.

Year

• 2004

Date created

• 2004-01-01

Resource type

• Major Qualifying Project

Major

• Chemistry

Rights statement

• In Copyright