Design of a Scalable Method to Produce Cardiogenic Cells from hMSCs through Embryoid Body Formation and PDGF TreatmentPublic
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This project developed a scalable method to produce cardio-myocytes from human mesenchymal stem cells (hMSCs) for use as a therapy for myocardial infarctions. Embryoid bodies (EBs) formed from hMSCs produced cardiac cells. To increase the production of EBs, a non-adhesive well structure was developed and tested. To increase the percentage of cardiac cells resulting from the process, platelet derived growth factor was used as a supplement. These novel methods will ease the process and increase the yield of cardiac cells.
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