Rab GTPases regulate vesicle trafficking in the cell and there are 37 functionally distinct members. This project began a molecular cloning library to facilitate a proteome wide quantitative analysis. This is the start of determining which RAB interactions are bona fide, which are not and give an insight into modes specificity. It will propel a structural study of Rab GTPases. This work clarifies a possible interaction between a Rab and an effector and shows the novel crystal structure of Rab33b.

• This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.

Creator

• Ritacco, Christopher John

Publisher

• Worcester Polytechnic Institute

Identifier

• 03D181M

Advisor

• Hobey, William D.

Year

• 2003

Date created

• 2003-01-01

Resource type

• Major Qualifying Project

Major

• Biochemistry

Rights statement

• In Copyright