Student Work

Bile acid-induced apoptosis in a MDCK cell line transfected with the hepatocyte sinusoidal bile acid transporter

Public

Downloadable Content

open in viewer

The objective of this project is to determine if the canine kidney cell line (MDCK) transfected with the gene for the hepatocyte sinusoidal transporter (Ntcp) would be a useful model for rat hepatocytes in studying bile acid-induced apoptosis. In order to verify this cell line as a beneficial model, several experiments involving bile acids and cyclic adenine monophosphate were performed. A comparison of these results with those performed on hepatocytes indicate that MDCKs are valuable in studying bile acid-induced apoptosis.

  • This report represents the work of one or more WPI undergraduate students submitted to the faculty as evidence of completion of a degree requirement. WPI routinely publishes these reports on its website without editorial or peer review.
Creator
Publisher
Identifier
  • 99D141M
Advisor
Year
  • 1999
Sponsor
Date created
  • 1999-01-01
Resource type
Major
Rights statement
License

Relations

In Collection:

Items

Items

Permanent link to this page: https://digital.wpi.edu/show/df65vb78w